Kiora Pharmaceuticals, Inc. is a clinical-stage specialty pharmaceutical company focused on developing therapies for orphan retinal diseases. Their lead product, KIO-301, aims to restore vision in patients suffering from retinitis pigmentosa (RP) through a novel mechanism involving a small molecule that selectively activates viable retinal cells no longer receiving signals due to the degeneration of photoreceptors. The company has received orphan drug designation from the FDA for KIO-301 and is in the process of advancing this therapy through clinical trials, with partnerships formed for its further development and potential commercialization.
In addition to KIO-301, Kiora is developing KIO-104 for non-infectious posterior uveitis and KIO-101 for ocular manifestations of autoimmune diseases, indicating a broader pipeline that addresses various ocular disorders. The company is strategically pursuing collaborations to enhance its research and development capabilities, aiming to bring innovative treatment options to market for patients with significant unmet needs in ophthalmology, thereby positioning itself as a valuable player in the specialty pharmaceuticals sector.